OverviewGenes and environment are the two primary factors in determining our health. The international community has spent billions of dollars sequencing the human genome (or at least one version of it) to understand our basic genetic makeup. Each of us carries a slightly different version of the human genome--on average varying by about 0.1% from the sequenced reference standard. Most human genetic variation results from tens of millions of single nucleotide polymorphisms (SNPs) or single characters of DNA, which tend to vary from person to person. The genetics research community is focusing much of its research on understanding how SNPs are linked with specific disease risks and outcomes so that it can develop better therapies and more predictive diagnostics. Unfortunately, the research has been hampered by the high cost of discovering and detecting large numbers of relevant SNPs.
The suite of ParAllele technologies is suitable for addressing a wide variety of genetics applications, including the following:
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